We offer testing on more than 100 different compounds using more than 20 different types of testing. Our instrumentation is extensive to cover all of this. Testing includes: FTIR (identification; primarily for raw materials), and wet chemistry identification.


Verification of potency claims by liquid chromatography is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture.  Dyad Labs utilizes compendial methods, AOAC validated test methods and analytical methods developed by Dyad through its years of experience in product testing.


Ultra-high performance liquid chromatography (UPLC) has evolved from high performance liquid chromatography (HPLC). Both techniques involve liquid chromatography used to separate the components from mixtures. UPLC differs from HPLC because smaller particle size columns are used.  With smaller-particles sizes, there is increased pressure and the instrumentation itself is designed to allow for that.  Smaller particle sizes allow for increased chromatographic efficiency and therefore a better and more resolved separation of peaks.  With narrower peak shapes, run time can be decreased.  All nine of our chromatographic systems at Dyad utilize UPLC instead of HPLC.  Assays that we conduct with UPLC/UV detection include:

  • Amino acids

  • Creatine and related compounds

  • Water-soluble vitamins

  • Organic acids

  • Fat-soluble vitamins

  • Alkaloids (already referenced in water soluble vitamin section)

  • Caffeine, theophylline, theobromine, catechins, theacrine, BHB

  • Curcuminoids, ginsenosides, resveratrol


LC-MS/MS combines the separation of components using liquid chromatography with the detection specificity of mass spectrometry.  With all of the matrices we analyze and the complexity of them, this is a powerful technique. Compared to HPLC & UPLC, LC-MS/MS’s added specificity is especially critical in analysis of finished good with low concentrations of compounds, although raw materials can be analyzed just as well. Combined with the specificity, because of the added sensitivity, samples can be diluted relatively more than occurs using UV detection, thus allowing mitigation of sample matrix problems.  Some of the assays we analyze on these instruments include:

  • Protein identification (whey, casein, pea, soy, rice)
  • Methyl and cyanocobalamin
  • Melamine
  • Low concentrated water-soluble vitamins

  • Fat-soluble vitamins (Vitamins D2, D3, K1,
    and K2: menaquinone-4 and -7)